Main publications - Invited conferences

Le Noir S, Boyer F, Lecardeur S, Brousse M, Oruc Z, Cook J, Denizot Y, Cogné M. Functional anatomy of the immunoglobulin heavy chain 3΄ super-enhancer needs not only core enhancer elements but also their unique DNA context. Nucleic Acids Res. 2017, 45:5829-5837.

Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier JC, Laffleur B, El Makhour Y, Ryffel B, Quesniaux V, Togbé V, Mergny JL, Cook-Moreau J, Cogné M. G-quadruplex DNA targeting alters class switch recombination in B cells and attenuates allergic inflammation. J Allergy Clin Immunol. 2018, 142:1352-1355.

B Wehbi, C Oblet, F Boyer, A Druilhe, F Paraf, E Cogné, J Moreau, Y El Makhour, M Van Egmond, M* Cogné, Aldigier JC* (*co-senior authors) Mesangial deposition can strongly involve innate-like IgA molecules lacking affinity maturation. J Am Soc Nephrol. 2019 ;30:1238-1249.

Dalloul I, Boyer F, Dalloul Z, Pignarre A, Lacombe G, Fest T, Chatonnet F, Delaloy C,  Durandy A, Aldigier JC, Cook-Moreau J, Cogné M. Locus Suicide Recombination actively occurs on the functionally rearranged IgH allele in human B-cells. Plos Genetics. 2019 15(6):e1007721. doi: 10.1371/journal.pgen.1007721.

Quelven I, Monteil J, Sage M, Saidi A, Mounier J, Bayout A, Garrier J, Cogne M, Durand-Panteix S. (* co-senior authors). 212Pb α-Radioimmunotherapy Targeting CD38 in Multiple Myeloma: A Preclinical Study. J Nucl Med. 2020 Jul;61(7):1058-1065. doi: 10.2967/jnumed.119.239491. Epub 2019 Dec 20.

Le Noir S,  Bonaud A, Hervé B, Baylet A, Boyer F, Lecardeur S, Oruc Z, Sirac C, M Cogné. IgH 3’ Regulatory Region increases ectopic Class Switch Recombination. Plos Genetics. 2021, Feb 8;17(2):e1009288. doi: 10.1371/journal.pgen.1009288

Reizine F, Lesouhaitier M, Gregoire M, Pinceaux K, Gacouin A, Maamar A, Painvin B, Camus C, Le Tulzo Y, Tattevin P, Revest L, Le Bot A, Ballerie4 A, Cador- Rousseau B, Lederlin M, Lebouvier T, Launey Y, Latour M, Verdy C, Rossille D, Le Gallou S, Dulong J, Moreau C, Bendavid C, Roussel M, Cogné M, Tarte K, Tadié JM. ARS-CoV-2 induced ARDS associates MDSC expansion and lymphocyte dysfunction due to arginine shortage. J. Clin. Immunol. 2021 Apr;41(3):515-525. doi: 10.1007/s10875-020-00920-5

Roussel M, Ferrant J, Reizine F, Le Gallou S, Dulong J, Carl S, Lesouhaitier M, Gregoire M, Bescher N, Verdy C, Latour M, Bézier I, Cornic M, Vinit A, Monvoisin C, Sawitzki B, Leonard S, Paul S, Feuillard J, Jeannet R, Daix T, Tiwari VK, Tadié JM, Cogné M &Tarte K (*co-senior authors). Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV2 infection. Cell Report Medicine 2021, May 6:100291. doi: 10.1016/j.xcrm.2021.100291.

Dalloul I, Laffleur B, Dalloul Z, Wehbi B, Jouan F, Brauge B, Derouault P, Cook-Moreau J, Kracker S, Fischer A, Durandy A, Le Noir S, Cogné M. UnAIDed Class-Switching in activated B-cells reveals intrinsic features of a self-cleaving IgH locus. Frontiers in Immunology 2021, Oct 28;12:737427. doi: 10.3389/fimmu.2021.737427. eCollection 2021

Javaugue V, Pascal V, Bender S, Nasraddine S, Dargelos M, Alizadeh M, Saintamand A, Filloux M, Derouault P, Bouyer S, Desport E, Jaccard A, Bridoux F, Cogné M*, Sirac C* (co-corresponding authors). RNA-based Immunoglobulin Repertoire Sequencing (RACE-RepSeq): A new tool for the management of monoclonal gammopathy of renal significance. Kidney int 2021 Nov 9:S0085-2538(21)01033-4. doi: 10.1016/j.kint.2021.10.017.

Durand-Panteix S, Monteil S, Sage M, Garot A, Clavel M, Saidi A, Torgue J, Cogné M* & I Quelven* (*co-corresponding authors). Preclinical study of 212Pb alpha-radioimmunotherapy targeting CD20 in non-Hodgkin lymphoma. Br. J. Cancer. 2021 2021 Dec;125(12):1657-1665. doi: 10.1038/s41416-021-01585-6.

Rogier M, Moritz J, Robert I, Lescale C, Heyer V, Abello A, Martin O, Capitani K, Thomas M, Thomas-Claudepierre AS, Laffleur B, Jouan F, Pinaud E, Tarte K, Cogné M, Conticello SG, Soutoglou E, Deriano L, Reina-San-Martin B. Fam72a enforces error-prone DNA repair during antibody diversification. Nature 2021, Dec;  600 (7888); 329-33312:737427. doi: 10.1038/s41586-021-04093-y.

Ueda*, N, Cahen M* (*equal contribution) , Danger Y, Moreaux J, Sirac S, Cogné M. Immunotherapy perspectives in the new era of B-cell Editing. Blood Adv. 2021 (in press)

Dalloul Z, Best M, Chenuet P, Dalloul I, Le Noir S, Togbé D, Gador M, Ryffel B, Quesniaux V, El Makhour Y, Boyer F, Aldigier JC, Cook-Moreau J, Fazilleau N & Cogné M. BET inhibition of IgG/IgE production in murine B cells is counter-balanced by a strong Th2 bias. Clinical and Translational Immunology. DOI:10.1002/cti2.1280 (2021, in press)

F. Denis,  M. Cogné, L. Belec : "Femme enceinte et défense immunitaire anti-virale"
    Dans : ”Les virus transmissibles de la mère à l’enfant”, Med/Sci, John Libbey, Paris 1999, pp24-56.

M. Cogné :  "Immunité humorale. Lymphocytes B ; immunoglobulines (structure, focntion, diversité ; investigation clinique ; concept de déficit inné de l’immunité humorale)"
    Dans : Revue du Praticien. 2001 Jan 31;51(2):193-202.

M. Cogné, HR. Galea, C. Sirac and C. Decourt : "Immunoglobulin decreased solubility diseases: pathologies of the V domains?"
    In: "Monoclonal gammopathies and the kidney" Karger press, G. Touchard and P. Ronco eds, 2002.

M. Cogné : "La saga des immunoglobulines: des protéines aux millions de formes"
     Dans : "Microscoop" 2003.

M. Cogné : "Immunoglobulines monoclonales"
    Dans : "Revue du Praticien". 2004 May 15;54(9):1019-24.

L. Delpy, C. Sirac et M. Cogné : "Le silence des allèles exclus… et la surveillance non canonique des ARNm d’immunoglobulines"
    Dans : "SFI Actualités". Juin 2004, 107 : p9-10.

M. Cogné and B.K. Birshtein : "Regulation of class switch recombination"
    In: "Molecular biology of B cells". T. Honjo, M.S. Neuberger and F.W. Alt eds, Elsevier Academic press, 2004.

M. Cogné : Chapître 4 , "Immunosénescence"
    Dans : "Vieillissement : les données biologiques" Ed F. Denis. Elsevier, 2005.

F. Bridoux, C. Sirac, A. Jaccard, RA. Ayache, JM. Goujon, M. Cogné and G. Touchard: "Renal Disease in cryoglobulinemic vasculitis"
     In: "The Kidney in systemic autoimmune diseases". JC Mason and CD Pusey eds, pp216-240. Elsevier. 2008.

M. Cogné, S. Duchez, V. Pascal : "Transgenesis and humanization of murine antibodies"
    Dans : "Médecine / Sciences" (Paris). 2009, 25:1149-54.

C. Sirac, F. Bridoux, M. Essig, O. Devuyst, G. Touchard and M. Cogné. "Toward understanding renal Fanconi syndrome: step by step advances through experimental models". In “ Experimental models for Renal Disease: Impact on Understanding Pathogenesis and improving Diagnosis”, Herrera GA. Eds Karger AG-Medical and Scientific Publishers
    In: "Contrib Nephrol". 2011;169:247-61.

E. Pinaud, M. Marquet, R. Fiancette, S. Péron, C. Vincent-Fabert, Y. Denizot, M. Cogné : "The IgH locus 3’ regulatory region : pulling the strings from behind".
    In: "Advances in Immunology" 2011; 110:27-70

B. Laffleur, V. Pascal, C. Sirac, M. Cogné : "Production of human or humanized antibodies into mice".
    In: "Methods in molecular biology" 2012 , 901:149-59

V. Pascal, B. Laffleur and M. Cogné : "Class-specific effector functions of therapeutic antibodies".
    In: "Methods in molecular biology" 2012;901:295-317

S. Péron, B. Laffleur, N. Denis-Lagache, J. Cook-Moreau, M. Filloux, M. Cogné : "IgH locus suicide recombination or Whan B cells surrender !"
     Dans : "Médecine / Sciences" (Paris). 2012, 28 : 551-4

M. Cogné : "Activation-induced deaminase (AID) in B lymphocyte maturation and beyond".
    In: "Biomedical Journal". 2013, (in press)

B. Laffleur, Z. Dalloul, I. Dalloul, S. Le Noir, M. Cogné :  "When immunoglobulin genes assemble with bricks from other chromosomes".
    Dans : "Médecine / Sciences" (Paris). 2016;32:677-80

V. Pascal, M. Hiblot, B. Wehbi, JC. Aldigier & M. Cogné : "Homeostasis of IgA responses and microbiota"
    Dans : "Médecine / Sciences" (Paris). 2021 Jan;37(1):35-40.

Invited conference : Congrès annuel de la Société Française d’Immunologie,Paris, France, «IgG5 a new human antibody class», décembre 2021.

Keynote lecture : Journées du Département d’Immunologie, Institut Pasteur Paris, 2022 May 23, Pornichet : «Alternate DNA breaks and other specific features of the human heavy chain locus».

Invited conference : Congress :« Antibody diversification and deaminases in Immunité and Cancer», Québec, 2022